Andy Murray misplaced to Aslan Karatsev within the final 16 of the Zhuhai Championships in China.
The Russian, who reached the 2021 Australian Open semi-finals as a qualifier, got here via 4-6 6-3 6-2.
Murray led 5-2 within the opening set and held off a Karasev fightback to take it however the world quantity 63 was the stronger after that.
The veteran Scot misplaced his serve twice within the second and third units as Karatsev wrapped up the victory.
It made it two wins out of two for Karatsev, who had additionally overwhelmed Murray of their solely earlier profession assembly within the 2022 Sydney Traditional ultimate.
Karatsev will face one other Briton within the final eight after Cameron Norrie swept previous Australian qualifier Marc Polmans 6-0 6-3.
The world quantity 17 gained 90% (26/29) of his first-serve factors and didn’t face a break level on his approach to victory as he chases his second title of the season.