Plymouth Argyle have been drawn at residence to eight-time winners Liverpool within the FA Cup fourth spherical.
Argyle, backside of the Championship, beat Premier League aspect Brentford 1-0 on Saturday within the largest shock of the weekend.
League One leaders Birmingham will host Newcastle, whereas fellow third-tier aspect Exeter will play at residence to Nottingham Forest.
Holders Manchester United, who beat Arsenal on penalties to achieve spherical 4, will play 2021 winners Leicester.
There are three different all-Premier League ties, with Tottenham travelling to Aston Villa, Brighton enjoying Chelsea and Bournemouth travelling to Everton.
Manchester Metropolis will go to both Leyton Orient or Derby County, who play their third-round tie on Tuesday after having their recreation postponed on Saturday due to a frozen pitch – whereas Crystal Palace journey to League Two aspect Doncaster.
Nationwide League outfit Dagenham & Redbridge, the lowest-ranked aspect remaining within the competitors, will face Leeds in the event that they beat Millwall of their third-round tie on Monday.
The ties will likely be performed over the weekend of Saturday, 8 February.